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• S4.E1 ∙ John Krasinski/Yvonne Orji
• S4.E2 ∙ Rob Lowe/John Kerry/Kathleen Madigan
• S4.E3 ∙ Emma Thompson/Troye Sivan
• S4.E4 ∙ Sharon Osbourne/Kathleen Madigan/Jay Rock
• S4.E5 ∙ Bob Woodward/The Knocks/Foster the People
• S4.E6 ∙ Neil deGrasse Tyson/Michael Rapaport
• S4.E7 ∙ Keira Knightley/Beto O'Rourke/Martha Stewart
• S4.E8 ∙ John Heilemann/Alex Wagner/Judy Greer/First Aid Kit
• S4.E9 ∙ Anna Kendrick/Anne-Marie
• S4.E10 ∙ Admit It... You Forgot This Happened
• S4.E11 ∙ Jane Fonda/Willie Nelson
• S4.E12 ∙ Tiffany Haddish/Iain Armitage
• S4.E13 ∙ Hillary Rodham Clinton/Neil deGrasse Tyson
• S4.E14 ∙ Emma Stone/Flight of the Conchords
• S4.E15 ∙ America Ferrara/Nas
• S4.E16 ∙ Candice Bergen/Jacinda Ardern/Jon Batiste
• S4.E17 ∙ Jeff Bridges/Cedric the Entertainer
• S4.E18 ∙ Kristen Bell/Mark Leibovich/Nik Dodani
• S4.E19 ∙ Jake Tapper/Eric Idle/Lauv/Julia Michaels
• S4.E20 ∙ Eva Longoria/Damon Wayans Jr/Steve Kornacki
• S4.E21 ∙ Nick Kroll/Jodie Whittaker/Cat Power
• S4.E22 ∙ Lady Gaga/Caitlin Peluffo
• S4.E23 ∙ Ellie Kemper/Sam Elliott
• S4.E24 ∙ Melissa McCarthy/Phoebe Robinson
• S4.E25 ∙ Lin-Manuel Miranda/Brooke Baldwin/Laura Benanti
• S4.E26 ∙ Peter Dinklage/Busy Phillipps/Noname
• S4.E27 ∙ Joe Scarborough/Mika Brzezinski/Laura Benanti/The Revivalists
• S4.E28 ∙ Robin Wright/Caitlin Peluffo/Hillary Clinton/Melissa McCarthy
• S4.E29 ∙ Sarah Silverman/Scott Bakula/Transviolet
• S4.E30 ∙ Jon Faveau/Jon Lovett/Tommy Vietor/Charlamagne Tha God
• S4.E31 ∙ Gerard Butler/Rowan Atkinson/Ina Garten
• S4.E32 ∙ Gayle King/Kayli Carter/Andrea Bocelli/Matteo Bocelli
• S4.E33 ∙ Phil McGraw/Kayli Carter/Janelle Monae
• S4.E34 ∙ Kerry Washington/Taylor Mac
• S4.E35 ∙ Sarah Jessica Parker/Nancy Pelosi/Christine and the Queens
• S4.E36 ∙ Mike Myers/Christiane Amanpour
• S4.E37 ∙ Chris Wallace/Cole Sprouse/Tony Bennett
• S4.E38 ∙ Billy Eichner/Itzhak Perlman
• S4.E39 ∙ Jude Law/Amy Klobuchar/Flynn McGarry
• S4.E40 ∙ John Heilemann/Alex Wagner/Hasan Minhaj
• S4.E41 ∙ Chris Pine/Major Garrett/Triumph, The Insult Comic Dog
• S4.E42 ∙ Billy Crystal/Kirsten Gillibrand/Big Red Machine
• S4.E43 ∙ Alexander Skarsgard/Triumph, The Insult Comic Dog/Big Red Machine
• S4.E44 ∙ Hugh Jackman/Jeff Tweedy/Six-String Soldiers
• S4.E45 ∙ Rachel Weisz/Jason Mantzoukas/Demetri Martin/Dolph Lundgren
• S4.E46 ∙ Ricky Gervais/Bianna Golodryga/Flynn McGarry
• S4.E47 ∙ Ben Stiller/Jemele Hill/Jorja Smith
• S4.E48 ∙ Timothee Charlamet/Sonia Sotomayer/Graham Kay
• S4.E49 ∙ Millie Bobby Brown/Anthony Salvanto/Josh Groban
• S4.E50 ∙ Michael Douglas/Ben Sasse/Jose Andres